#6161st of 92 in Agent platformsFor science, health and research, science, research and papers

openscience

Research agent that reads papers, runs code and experiments, and logs every step

Stars
4.4k
License
Apache-2.0
Last commit
Oct 2026
Last release
Oct 2026
Language
TypeScript

Missed the latest GitHub check; these facts may be older.

Overview

OpenScience is a research agent with a workbench around it, shipped as an Electron desktop app, a browser workspace and a CLI. It plans a task, searches literature and databases such as PubMed, arXiv, ChEMBL and UniProt, runs code in shell, Python and R kernels, and returns results with a full trace. Compute can be local, Modal, SSH hosts, or Slurm and PBS clusters, with approval before jobs run.

Who it is for: Scientists and ML researchers doing literature review and data analysis

Strengths

  • Full trace of searches, code runs and file writes for each turn
  • Hundreds of bundled science skills plus connectors to PubMed, arXiv, ChEMBL, UniProt
  • Remote compute on Modal, SSH, Slurm or PBS, approved before jobs run
  • Works with own API keys, local models via Ollama or LM Studio, or Ace

Weaknesses

  • First-run setup asks you to sign in to an OpenScience account
  • Skills are mostly third-party; a skill does not guarantee its tools are installed
  • NVIDIA BioNeMo adapters are experimental and need your own NVIDIA key
  • Published benchmarks use GPT-6 models, not open-weight ones

What it needs

  • GPU optional
  • Needs Node/npm (CLI install), Bun (build from source), Modal, SSH or Slurm/PBS (optional remote compute)
  • Models: Provider API keys, Ollama, LM Studio, OpenAI-compatible local endpoints, OpenRouter

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